Polynucleotides
Improves thin, crepey skin. Often used for tired under-eyes.
- Treatment time
- 45 minutes
- Sessions
- Course of 2–3, 3–4 weeks apart
- Price
- £250 per 2ml

Skin booster
Polynucleotides are a regenerative treatment that improves the quality of the skin, often used for tired, crepey under-eyes. We use Plinest polynucleotides at our nurse-led clinic in Shirley, Solihull.
Book a ConsultationPolynucleotides are purified DNA fragments, injected into the skin to support its natural repair and improve its quality over time.
They are usually derived from purified salmon or trout DNA, so we always ask about fish allergies first. They don't add volume or change the shape of the area.

Polynucleotides aim to improve thin, crepey under-eye skin, so it looks smoother, firmer and less tired.
Because they work on the skin itself, the change is gradual. Many people notice the area looks smoother and brighter a few weeks after their second session.
They suit thin, crepey skin best, especially under the eyes.
If pigmentation or hollowness is the main cause, a different or combined plan may work better. Polynucleotides aren't given during pregnancy or breastfeeding, or to anyone with a fish allergy.
Book a ConsultationThe appointment takes about 45 minutes, and small bumps usually settle within a few hours.
We check your medical history and look closely at the area. Numbing cream can be applied first.
Minor bruising around the eyes is possible and usually fades within a few days. For 24 hours, avoid make-up, strenuous exercise and alcohol.
A course of two to three sessions, three to four weeks apart. A top-up every six to twelve months can help maintain the improvement.
Profhilo is a hyaluronic acid treatment that hydrates and firms the whole face. Polynucleotides are a regenerative treatment often used for the delicate under-eye area. Some people benefit from both.
Every new patient starts with a £50 New Patient Consultation, which includes a full OBSERV 520x skin analysis. It shows what's happening beneath the surface, so your plan is based on what your skin needs.
Common questions about polynucleotides at our Solihull clinic.
They can improve thin, crepey skin that makes the area look darker, but on their own they don't treat pigmentation. Your skin analysis shows which applies to you.
Most people find it very manageable, especially with numbing cream. You may feel small pinches as the product is placed.
No. They are usually derived from fish DNA, so they aren't suitable if you have a fish allergy.
The improvement builds across the course. A top-up every six to twelve months can help maintain it.
At Aurum Medical Aesthetics, inside Anna Hudson Hair at 5 Farmhouse Way, Shirley, Solihull B90 4EH. There's free parking.
Every polynucleotide treatment at Aurum is carried out by Jabran Khan, an NMC registered independent nurse prescriber, or Dr Gadah Al-Ani, a GDC registered dentist trained in aesthetics.
Jabran has 16 years in nursing and a Level 7 Diploma in Cosmetic Injectables and Dermatology from Harley Academy, London.
Dr Gadah graduated in dentistry from the University of Birmingham and holds a Level 7 Diploma in Cosmetic Injectables from Harley Academy, London.
Book a ConsultationConsultations are £50 and include a full OBSERV 520x skin analysis.